SR-121463A CAS; 185913-79-5

價(jià)格:12000元/公斤 含量:99% 包裝:25公斤
CAS;185913-79-5
分子式：C17H22ClNO3
分子量：323.8228
化學(xué)名稱(chēng) N-tert-Butyl-4-[5'-ethoxy-4-[2-(4-morpholinyl)ethoxy]-2'-oxospiro[cyclohexane-1,3'-

indolin]-1'-ylsulfonyl]-3-methoxybenzamide fumarate
The reduction of diethyl 3-(methoxymethoxy)glutarate (I) with LiAlH4 in THF gives 3-(methoxymethoxy)

pentane-1,5-diol (II), which is treated with Ts-OH and TEA in THF to yield the disulfonate (III). The 

condensation of (III) with 5-ethoxyindolin-2-one (IV) by means of tBu-OK in THF affords the spiro compound 

(V), which is deprotected with HCl in methanol to afford the spiranic alcohol (VI). The oxidation of (VI) 

with pyridinium chlorochromate (PCC) over Al2O3 provides the spiranic cyclohexanone (VII), which is treated 

with 2-chloroethanol (VIII) and Ms-OH in toluene to give the ketal (IX). The reaction of (IX) with zinc 

borohydride and trimethylsilyl chloride in ethyl ether/dichloromethane yields the 2-chloroethoxy derivative 

(X), which is condensed with 4-(N-tert-butylcarbamoyl)-2-methoxybenzenesulfonyl chloride (XI) by means of 

tBu-OK in THF to afford the adduct (XII). Finally, the target compound is obtained by condensation of (XII) 

with morpholine (XIII) by means of NaI in DMF, followed by treatment with fumaric acid.
尼朦爾可素  包裝:50克/瓶 價(jià)格:1300元/瓶 紅色粉末
還陽(yáng)CAS號(hào)：171596-29-5  8600元/公斤
金陽(yáng) CAS號(hào)：54060-92-3 18850-57-5  4600元/公斤
新陽(yáng)   36-12-87  4600元/公斤
蝦青 CAS號(hào)：472-61-7   8600元/公斤 
CAS號(hào)：1445583-51-6
MAB-CHMINAC 1454266-19-3
5FADB     1715016-75-3 
FUB-AMB   1715016-76-4
CAS號(hào)：70434-92-3 CP 47,497 CAS號(hào)：952016-47-6 8492312-32-2
CAS號(hào)：84485-00-7 1216544-25-0 125494-59-9 CAS：16359-54-9 CAS：18305-29-8
原料與成品三包服務(wù): CAS:90717-16-1;299-42-3;6740-85-81867-66-9;51062-14-7; CAS:2114-00-3;2011-67-8;5650-44

-2;103-79-7 CAS:4468-48-8;103-79-7;51-57-0;6740-88-1;936-59-4;60124-79-0;125-79-1 CAS:76-99-3;118-92-

3;2538-50-3;340-56-7;82-58-6;51753-57-2;58-08-2